END2CANCER:

Emerging Nanotechnology & Drug Delivery Applications for Cancer

December 6-7, 2018, Oklahoma City, Oklahoma

The University of Oklahoma Health Sciences Center and Stephenson Cancer Center are proud to host the 2018 “END2CANCER: Emerging Nanotechnology and Drug Delivery Applications for Cancer” conference from December 6-7, 2018 in Oklahoma City, Oklahoma, USA.

The focus of the two-day conference is to bridge laboratory research conducted in the areas of nanotechnology and drug delivery to clinical application for the detection, diagnosis, imaging, and treatment of cancer. The conference will bring together leaders in the field who will discuss new and emerging concepts and technologies and challenges in clinical advancement.

Topics in modulating the tumor microenvironment and harnessing the immune system for improved drug delivery and therapy will also be covered in planned thematic sessions. Finally, funding opportunities for cancer nanomedicine from the National Cancer Institute/National Institutes of Health will be presented.

The multi-disciplinary conference will bring together physicians, basic scientists, engineers, physicists, chemists, post-doctoral fellows, high-school and college students, patient advocates, business professionals, educators, and technology transfer specialists. Students and fellows will have an opportunity to present their work as a poster presentation and compete for awards.

A special education session titled “Meet The Investigators” is planned for students, fellows, and young investigators to network and exchange ideas and offer collaborative opportunities during the two-day meeting.

The organizing committee would like to invite you to visit the “Sooner” state of Oklahoma and participate in this exciting conference.

2017 END2CANCER CONFERENCE

The inaugural “END2CANCER: Emerging Nanotechnology and Drug Delivery Applications for Cancer” conference was held on December 14-15, 2017 in Oklahoma City, Oklahoma, USA.

Click to view last year’s Program Book.

2017 Sponsors

2017 SCHEDULE OF EVENTS

Registration & Breakfast / Meet The Investigators Session

Meet the Investigators session for students, postdocs, fellows, and junior faculty by advance registration only. Please indicate on the conference registration link. Breakfast for other attendees will be served at the Samis Education Center.

60mins

Andrews Academic Tower, Conference Room B, 800 Stanton L. Young Blvd., Oklahoma City, OK 73104

Pre-Registration Required

Dr. Rajagopal Ramesh

Introduction

5mins

Samis Conference Room

Dr. Rajagopal Ramesh

Professor, University of Oklahoma Health Sciences Center

Dr. Jason Sanders; Dr. James Tomasek

Welcome

10mins

Samis Conference Room

Dr. Jason Sanders; Dr. James Tomasek

Dr. Jason Sanders, (Provost, OUHSC); Dr. James Tomasek, (Vice-President of Research, University of Oklahoma Health Sciences Center)

Kelvin Droegemeier

Bioengineering

5mins

Samis Conference Room

Kelvin Droegemeier

Vice-President of Research, University of Oklahoma

Dr. Robert Mannel

Nanomedicine & Cancer

5mins

Samis Conference Room

Dr. Robert Mannel

Director, Stephenson Cancer Center

Dr. Rajagopal Ramesh

Keynote Speaker Introduction

5mins

Samis Conference Room

Dr. Rajagopal Ramesh

Professor, Department of Pathology, Director, Experimental Therapeutics and Translational Cancer Medicine, University of Oklahoma Health Sciences Center

Omid Farokhzad

Keynote Speaker

Omid Farokhzad, (Professor of Medicine and Director of Nanomedicine, Harvard Medical School), "Polymeric Nanoparticles: Tumor Microevironment Variability and Implications for Nanoparticle Design and Development"

45mins

Samis Conference Room

Omid Farokhzad

Professor of Medicine and Director of Nanomedicine, Harvard Medical School

Moderators (Dr. Song Li & Sharukh S. Khajotia)

Session I – Nucleic Acids Origami

9:20 am - 9:50 am: Plenary Speaker, Peixuan Guo (Professor, College of Pharmacy, Ohio State University), "The Advancement of the Emerging Field of RNA Nanotechnology"

9:50 am - 10:10 am: Nathaniel S. Green (Assistant Professor, Department of Chemistry, Northeastern Oklahoma State University), "DNA-based Multiplexed Biosensing: Challenges and Opportunities"

10:10 am -10:30 am: Carlos Castro (Assistant Professor, Department of Mechanical and Aerospace Engineering, Ohio State University), "DNA Origami Nanodevices for Delivery and Detection Applications"

10:30 am -10:50 am: David Oupicky (Professor, Department of Pharmaceutical Sciences, University of Nebraska Medical Center), "CXCR4-inhibiting Nanocarriers for Nucleic Acid Therapy of Metastatic Cancer" 

90mins

Samis Conference Room

Moderators (Dr. Song Li & Sharukh S. Khajotia)

Coffee Break

10mins

Samis Conference Room

Moderators (Dr. Jinming Gao & Dr. Han Yuan)

Session II – Molecular & Diagnostic Imaging

11:00 am - 11:30 am: Plenary Speaker, Samuel Achilefu (Professor and Co-Director, Center for Nanomedicine, Washington University, St. Louis), "High Throughput Surgery Using Cancer Goggles"

11:30 am - 11:50 am: Rheal Towner (Professor, Oklahoma Medical Research Foundation), "Molecular-Targeted Magnetic Resonance Imaging (mtMRI) as a Tool to Assess Gliomas and Potential Therapeutic Agents"

11:50 am - 12:10 pm: Kimberly Kelly (Associate Professor, Department of Radiology, University of Virginia), "Hitting the Target: Imaging, Nanotechnology, and Drug Delivery in Pancreatic Cancer"

12:10 am - 12:30 pm: Hong Liu (Professor, Department of Electrical Engineering, University of Oklahoma), "Clinical Potential of Phase Sensitive X-Ray Imaging for Breast Cancer Diagnosis"

12:30 pm - 12:50 pm: Bin Zheng (Professor, Department of Electrical Engineering, University of Oklahoma), "Assessment of Cancer Risk and Prognosis Using New Quantitative Imaging Markers"

110mins

Samis Conference Room

Moderators (Dr. Jinming Gao & Dr. Han Yuan)

Lunch Break & Poster Competition Session

(Judges: 2 external and 2 internal – TBD)

70mins

Samis Conference Room

Moderators (Dr. Xiaoming He & Dr. Youngjae You)

Session III – Drug Delivery

2:00 pm – 2:30 pm: Plenary Speaker, Miqin Zhang (Professor, Department of Material Science and Engineering, University of Washington), "Iron Oxide Nanoparticles for Targeted Gene Therapy"

2:30 pm – 2:50 pm: Stefan Wilhelm (Assistant Professor, School of Biomedical Engineering, University of Oklahoma), "Quantifying Nanoparticle Delivery to Solid Tumors"

2:50 pm – 3:10 pm: Chalet Tan (Associate Professor, Department of Pharmaceutics and Drug Delivery, University of Mississippi), "Concurrent Delivery of MicroRNA and Chemotherapy via Biodegradable Nanocarriers for the Treatment of KRAS Mutant Cancer"

3:10 pm – 3:30 pm: Juliane Nguyen (Assistant Professor, Department of Pharmaceutical Sciences, State University of New York), "Nucleic Acids Going POSTAL - Therapeutic Applications of Actively-Loaded Exosomes"

3:30 pm – 3:50 pm:  Josh D. Ramsey (Associate Professor, Department of Chemical Engineering, Oklahoma State University), "Genes and Proteins: How Do We Deliver Macromolecular Drugs?"

3:50 pm – 4:10 pm: Chuanbin Mao (Professor, Department of Chemistry, University of Oklahoma), "Phage-Based Nanomedicine: From Probes to Therapeutics"

130mins

Samis Conference Room

Moderators (Dr. Xiaoming He & Dr. Youngjae You)

Coffee Break

10mins

Samis Conference Room

Moderators (Dr. Mansoor Amiji, & Dr. Yolanda Vasquez)

Session IV – Cancer Gene & Drug Therapy

4:20 pm - 4:50 pm:  Plenary Speaker, Tatiana Bronich (Professor and COBRE Nano Director, Department of Pharmaceutical Sciences, Nebraska Medical Center), "Soft Nanomaterials for Drug Delivery in Cancer"

4:50 pm - 5:10 pm:  Xiaohu Gao (Professor, Department of Biomedical Engineering, University of Washington), "Translational Nanotechnology for Sensitive Analysis of Disease Biomarkers"

5:10 pm - 5:30 pm:  Rajagopal Ramesh (Professor, Department of Pathology, University of Oklahoma Health Sciences Center), "Targeting the RNA-Binding Protein HuR for Cancer Therapy"

5:30 pm - 5:50 pm: Zhengrong Cui (Professor, Department of Pharmaceutical Sciences, University of Texas Austin), "Mechanisms of Overcoming Tumor Cell Resistance to Nucleoside Analogues through Nanotechnology"

90mins

Samis Conference Room

Moderators (Dr. Mansoor Amiji, & Dr. Yolanda Vasquez)

Transport from Conference to Petroleum Club

Transport of Invited Speakers & Attendees by Bus

45mins

Samis Conference Room

Piotr Grodzinski

Dinner at Petroleum Club

Welcome (7:10 pm - 7:15 pm) – Danny Dhanasekaran (Associate Director of Research, Stephenson Cancer Center)

Keynote Speaker Introduction (7:15 pm - 7:20 pm) – Lei Ding (Associate Professor, Department of Biomedical Engineering, OU Norman)

Keynote Speaker – NIH Perspective (7:20 pm – 8:05 pm) – Piotr Grodzinski (Program Director, Nanotechnology, National Cancer Institute), "Cancer Nanotechnology: Current Status and Future Opportunities - View from the NCI Alliance for Nanotechnology in Cancer"

180mins

Petroleum Club, Oklahoma City, OK

Piotr Grodzinski

Program Director, Nanotechnology, NCI

Transport Back to Hotel

Transport of Invited Speakers/Attendees back to Embassy Suites Hotel

10mins

Registration & Breakfast

60mins

Samis Conference Room

Dr. Thomas Landers

Welcome

5mins

Samis Conference Room

Dr. Thomas Landers

Dean College of Engineering, University of Oklahoma

Dr. Michael Detamore

Bioengineering Program at the University of Oklahoma

5mins

Samis Conference Room

Dr. Michael Detamore

Director School of Biomedical Engineering, University of Oklahoma

Dr. Wei Chen

Keynote Speaker Introduction

5mins

Samis Conference Room

Dr. Wei Chen

Professor, Department of Engineering and Physics; Director of Center for Interdisciplinary Biomedical Education & Research; Interim Dean, College of Mathematics and Science, University of Central Oklahoma

Xiaoyuan (Shawn) Chen

Keynote Speaker

Xiaoyuan (Shawn) Chen, (Senior Investigator, NIH/NIBIB, Bethesda, MD), "Albumin-Binding Evans Blue Derivatives as Cancer Theranostics"

45mins

Samis Conference Room

Xiaoyuan (Shawn) Chen

Senior Investigator, NIH/NIBIB, Bethesda, MD

Moderators (Dr. Tatiana Bronich & Dr. Wei Chen)

Session V – Nanotechnology & Tumor Microenvironment

9:05 am - 9:35 am – Plenary speaker Mansoor Amiji (Professor and Chair, Department of Pharmaceutical Sciences, Northeastern University, Boston), "Reprogramming of the Tumor Microenvironment by Exosomal Transfer of Nucleic Acid"

9:35 am - 9:55 am – Song Li (Professor, Department of Pharmaceutical Sciences, University of Pittsburgh), "An Immunostimulatory Dual-Functional Nanocarrier for Cancer Immunotherapy"

9:55 am – 10:15 am – Betty Kim (Associate Professor, Mayo Clinic, Jacksonville, Florida), "Designing Immune Modulating Nanomedicine for Cancer Therapy"

10:15 am – 10:35 pm – Ennio Tasciotti (Professor, Houston Methodist Hospital), "Targeting Cancer Inflammatory Microenvironment with Biomimetic Nanoparticles"

10:35 pm – 10:55 am – James J Moon (Assistant Professor, Department of Pharmaceutical Sciences, University of Michigan), "Nanodisc Vaccine Technology for Personalized Cancer Immunotherapy"

10:55 pm – 11:15 am - Vassilios Sikavitsas (Professor, Department of Engineering, University of Oklahoma), "Towards the Development of 3D In-Vitro Tumor Models Using Bioreactors and Biomimetic Scaffolds"

115mins

Samis Conference Room

Moderators (Dr. Tatiana Bronich & Dr. Wei Chen)

Coffee Break

15mins

Samis Conference Room

Moderators (Dr. Kimberly Kelly, & Dr. Rheal Towner)

Session VI – Theranostics

11:30 am - 12:00 pm: Plenary Speaker, Jinming Gao (Professor, Department of Oncology, Pharmacology, & Otolaryngology, UT Southwestern Medical Center), "pH Transistor Nanomedicine for Cancer Surgery and Immunotherapy"

12:00 pm - 12:20 pm: Xiaoming He (Associate Professor, Department of Biomedical Engineering, Ohio State University), "Microfluids Enabled Bottom-up Engineering of 3D Vascularized Tumor for Drug Discovery"

12:20 pm - 12:40 pm: Arti Shukla (Associate Professor, Department of Pathology and Laboratory Medicine, University of Vermont), "Role of Exosomes in Development of Mesothelioma"

12:40 pm - 1:00 pm: Ashish Ranjan (Associate Professor, Department of Veterinary Medicine, Oklahoma State University), "Focused Ultrasound-Mediated Chemo-immunotherapy of Solid Tumors"

90mins

Samis Conference Room

Moderators (Dr. Kimberly Kelly, & Dr. Rheal Towner)

Lunch Break

60mins

Moderators (Dr. Peixuan Guo & Dr. Vassilios Sikavitsas)

Session VII – Photonics & Photodynamic Therapy

2:00 pm – 2:30 pm: Plenary Speaker, Roger Harrison (Professor, Department of Engineering, Oklahoma University), "Photothermal Therapy of Cancer via Targeted Single-Walled Carbon Nanotubes"

2:30 pm – 2:50 pm: Jin Xie (Assistant Professor, Department of Chemistry, University of Georgia, Athens), "Nanoparticles to Mediate X-Ray Induced Photodynamic Therapy"

2:50 pm – 3:10 pm: Wei Chen (Professor, Department of Engineering and Physics; Director of Center for Interdisciplinary Biomedical Education & Research; Interim Dean, College of Mathematics and Science, University of Central Oklahoma), "Photoimmunotherapy for Cancer Using Immunologically Modified Carbon Nanotubes"

3:10 pm – 3:30 pm: Youngjae You (Associate Professor, Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center), "Light-Activatable Prodrugs for the Combination of Photodynamic Therapy and Site-Specific Chemotherapy: A Synergistic Combination for Complimentary PKPD Effects"

90mins

Samis Conference Room

Moderators (Dr. Peixuan Guo & Dr. Vassilios Sikavitsas)

Coffee Break

10mins

Samis Conference Room

Moderators (Dr. Ennio Tasciotti & Dr. Michael Detamore)

Session VIII – Novel Technologies & Applications in Cancer

3:40 pm - 4:10 pm: Plenary Speaker, Amy E. Herr (Distinguished Professor, Department of Bioengineering University of California, Berkeley), "Measuring Molecular-to-Cellular Heterogeneity Using Electrophoretic Cytometry"

4:10 pm - 4:30 pm: Shalini Prasad (Associate Professor, Department of Bioengineering, University of Texas at Dallas), "Wecantag Technology: Multi-Scale Sensing Approaches for Cancer Biomarker Diagnostics"

4:30 pm - 4:50 pm: Sundar Madihally (Associate Professor, Department of Chemical Engineering, Oklahoma State University), "Novel Therapeutic Strategy Using Multiaxial Fibers"

4:50 pm – 5:10 pm: Melchor J. Antuñano (Director, Civil Aerospace Medical Institute, Oklahoma City), "Aerospace Medicine Implications of Nanomedicine"

5:10 pm – 5:30 pm: Magdalena Bieniasz (Assistant Member, Oklahoma Medical Research Foundation), "Utilization of Patient-Derived Tumor Xenograft (PDX) Models in Oncology"

110mins

Samis Conference Room

Moderators (Dr. Ennio Tasciotti & Dr. Michael Detamore)

Award Ceremony & Closing Remarks

Awards Presentation to Fellows/Students/Young Investigator

10mins

Samis Conference Room

2017 KEYNOTE SPEAKERS

plus

Omid Farokhzad, MD, MBA

Harvard Medical School

plus

Xiaoyuan (Shawn) Chen

NIH/NIBIB, Bethesda, MD

plus

Piotr Grodzinski, PhD

Nanotechnology, NCI

2017 ORGANIZING COMMITTEE

Chairman

Rajagopal Ramesh, PhD
The University of Oklahoma Health Sciences Center

Members

Handan Acar, PhD
The University of Oklahoma

Wei Chen, PhD
University of Central Oklahoma

Michael Detamore, PhD
The University of Oklahoma

Lei Ding, PhD
The University of Oklahoma

Roger Harrison, PhD
The University of Oklahoma

Sharukh Khajotia, DDS, PhD
The University of Oklahoma Health Sciences Center

Min Li, PhD
The University of Oklahoma Health Sciences Center

Hong Liu, PhD
The University of Oklahoma

Vassilios Sikavitsas, PhD
The University of Oklahoma

Rheal Towner, PhD
Oklahoma Medical Research Foundation

Stefan Wilhelm, PhD
The University of Oklahoma

Youngjae You, PhD
The University of Oklahoma Health Sciences Center

Han Yuan, PhD
The University of Oklahoma

Bin Zheng, PhD
The University of Oklahoma

Coordinators

Claire Turmelle
The University of Oklahoma Health Sciences Center

Stevie Warner, MHR
The University of Oklahoma Health Sciences Center

ACCOMMODATIONS

The recommended conference hotel is located on the Oklahoma Health Center campus - within walking distance of the conference.

Embassy Suites by Hilton, Oklahoma City Downtown Medical Center

741 Phillips Ave.
Oklahoma City, OK 73104

RATES AVAILABLE SUMMER 2018

Register

Please contact Stevie Warner with any questions about the 2017 conference or the upcoming 2018 conference.

E: stevie-warner@ouhsc.edu

P: (405) 271-2537

Registration for the 2018 conference is not currently open. If you would like to be notified when registration is open, please submit your email address.

Press Release

Title
Authors Names and Affiliations
Abstract Limit: 300 Words Max
Presenting Author: Underline
Presenting Author: Email
Font: Times New Roman
Font Size: 12
Acknowledgement of Funding

Nanomedicine Journal

For more information on the latest in nano medicine, please visit the Nanomedicine Journal link below.